This randomized, double-blind, parallel controlled trial investigated the effects of daily consumption of coffee enriched in chlorogenic acids (CGA) on abdominal fat area. Healthy, overweight men and women (n = 150, BMI ≥ 25 to <30 kg/m²) were allocated to high-CGA (369 mg CGA/serving) or control (35 mg CGA/serving) coffee groups. Instant coffee was consumed once daily for 12 weeks, with four-week pre- and post-observation periods. Abdominal fat area and anthropometric measurements were analyzed at baseline and at 4, 8, and 12 weeks, and 142 subjects completed the trial.
Visceral fat area (VFA), total abdominal fat area (TFA), body weight, and waist circumference significantly decreased in the CGA group compared with the control group, with a group x time interaction (p < 0.001, p = 0.001, p = 0.025, and p = 0.001, respectively). Changes in VFA and TFA from baseline to 12 weeks were significantly greater in the CGA group than in the control group (-9.0 ± 13.9 cm² vs. -1.0 ± 14.3 cm², p < 0.001; -13.8 ± 22.9 cm² vs. -2.0 ± 16.2 cm², p < 0.001).
Consumption of high-CGA coffee for 12 weeks by overweight adults might lower abdominal fat, BMI, and waist circumference.
Watanabe T, Kobayashi S, Yamaguchi T, Hibi M, Fukuhara I, Osaki N. Coffee Abundant in Chlorogenic Acids Reduces Abdominal Fat in Overweight Adults: A Randomized, Double-Blind, Controlled Trial. Nutrients. 2019 Jul 16;11(7).