This randomized, single-blind, placebo-controlled study evaluated the effects on skin health of 6 weeks of oral supplementation with 100 mg/d of hydroalcoholic extract from Amorphophallus konjac tubers standardized to 5% glycosylceramides among 51 healthy human volunteers. The skin parameters were evaluated through dermatological diagnosis. Subject perceived efficacy of the product was further evaluated by a self-assessment questionnaire.

Results showed that oral supplementation with Amorphophallus konjac extract significantly decreased the skin dryness, hyperpigmentation, redness, itching and oilyness (p < 0.05). The improvement in skin health following intake of supplementation was observed to be time-dependent from the start. Further, Amorphophallus konjac extract was well-tolerated throughout the study, as no adverse events or toxic changes were recorded.

In conclusion this study demonstrates the skincare properties of orally ingested glycosyl ceramides from konjac tubers.

Heggar Venkataramana S, Puttaswamy N, Kodimule S. Potential benefits of oral administration of AMORPHOPHALLUS KONJAC glycosylceramides on skin health – a randomized clinical study. BMC Complement Med Ther. 2020;20(1):26.