This placebo-controlled, double-blind, matched-paired study assessed the impact of Eurycoma longifolia on the hypothalamic-pituitary-gonadal and hypothalamic-pituitary-adrenal axes in healthy young males (n=32) who received 600 mg/day of Eurycoma longifolia or placebo for 2 weeks.
Blood analysis showed significant interaction and time effects for testosterone (p = 0.005), free testosterone (p = 0.012) and estradiol (p = 0.008) levels in favour of the treatment group.
The raised testosterone level may be due to a greater rate of hormone production via the hypothalamic-pituitary-adrenal axis.
The raised testosterone following Eurycoma longifolia supplementation may benefit to muscle and strength gain in young adults.
Chan KQ, Stewart C, Chester N, Hamzah SH, Yusof A. The effect of Eurycoma Longifolia on the regulation of reproductive hormones in young males. Andrologia. 2021 Feb 9:e14001.