Cabinet Expert Scientifique et Réglementaire
Cabinet Expert Scientifique et Réglementaire
Toxicological studies was performed on mango leaf extract (Mangifera indica) containing 60% mangiferin (MLE). No evidence of genotoxicity was found in a bacterial reverse mutation test (Ames). While evidence of clastogenic activity was noted in an in vitro chromosomal aberration test, an …
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The aim of this study was to examine whether a lycopene supplementation can improve the spermatogram of infertile men with oligozoospermia. 44 men have been enrolled. The study was randomized, double blinded and placebo-controlled. The experimental group received 25 mg/day of lycopene. After 12 weeks of …
Read moreIn this randomized, double-blind controlled study, 30 healthy subjects were daily supplemented with either 1 mg or 30 mg of lycopene or 7mg of lycopène plus 10 g of dark chocolate or 10 g of dark chocolate. Supplementation was performed during 1 month. Results of the …
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This randomized, double-blind, parallel controlled trial investigated the effects of daily consumption of coffee enriched in chlorogenic acids (CGA) on abdominal fat area. Healthy, overweight men and women (n = 150, BMI ≥ 25 to <30 kg/m²) were allocated to high-CGA (369 mg CGA/serving) or control …
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Following the cases of cholestatic hepatitis associated to the consumption of products containing turmeric, the Italian Authorities published a modification of their list of plants (Decree of 26 July 2019 modifying the Decree of 10 August 2018) adding a mandatory warning …
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This meta-analysis focused on the effects of aronia consumption on several cardiovascular risk markers. The authors included 7 studies in the meta-analysis, and focused on lipid profile, blood pressure, and inflammatory markers. Results showed that aronia increases HDL lipoprotein (WMD = 1.48 mg/dL, …
Read moreIn this randomized, double-blind, placebo-controlled study, the effects of a supplementation with Lactobacillus rhamnosus GG on the prevention of neonatal hyperbilirubinemia due to isoimmunization was evaluated on 60 neonates. No significant difference was observed before 36h. No difference was observed on the duration of phototherapy, used in the treatment …
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A parallelized, randomized clinical study with 31 young healthy adults investigated the effects of a glucose solution (control group) or a glucose solution containing a guava fruit extract prepared by supercritical CO2 extraction (intervention group), during an oral glucose tolerance test (OGTT). Blood samples were collected prior to …
Read moreThis double-blind, randomized, placebo-controlled study, evaluated among 92 patients with non-alcoholic fatty liver disease (NAFLD) the effects of supplementation with either 3 g/d of turmeric or 9 g/d of infused chicory seed (4.5 g /100mL) or both turmeric and chicory …
Read moreThis randomized, double-blind, placebo-controlled study was conducted to assess the efficacy of supplementation during 84 days, with an Andrographis paniculata extract (300 or 600 mg/d), on osteoarthritis pain in 103 patients with knee osteoarthritis. Patients supplemented with 300 or 600 …
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Nutraveris
