- Interest of botanicals for COVID-19
COVID‐19 is spreading worldwide, leading a pandemic. This review highlighted that curcumin could be a new treatment option to combat the COVID‐19. Curcumin, an active constituent of Curcuma longa (turmeric), has some useful clinical effects such as antiviral, antinociceptive, anti‐inflammatory, antipyretic, and antifatigue effects that could alleviate symptoms of the infected patient with COVID‐19. Curcumin ...
- Review of the effects of probiotics in stimulating the immune system in the context of viral respiratory tract infection
Viruses that cause respiratory
tract infections are found in various virus families, which differ in virulence
and utilize variable strategies to infect the host cells and to evade the host
immune system. Among non-pharmacological solutions for the management of these
respiratory tract infections, probiotics have been proposed as an adequate
solution. Indeed, probiotics have been shown to modulate immune system ...
- Review of the impact of probiotics in the antiviral response in the context of the COVID-19 epidemic
This review is based on the correlation that has been previously reported
between SRAS-CoV-2 disease progression and the composition of the gut
microbiota demonstrating that some
patients with COVID-19 showed intestinal microbial dysbiosis, with a decrease
in cell numbers of Lactobacillus and Bifidobacterium.
In this context, this review is
focused on the potential of probiotics
and their metabolites to intervene with ...
- Review of the effects of compounds present in Nigella sativa seeds in the prevention and management of viral infections such as SARS-CoV-2 infection
This review was interested in the potential
of active compounds from Nigella sativa
on the suppression of chronic inflammation and the promotion of healthy immune
This review reported evidence of
beneficial effects of different Nigella
sativa preparations, mainly for preparation containing thymiquinone, alpha-hederin,
and nigellidine, against immune disturbance, autophagy
dysfunction, oxidative stress,
ischemia, inflammation, in several
COVID-19 comorbidities such as diabetes, cardiovascular disorders,
- Folic acid status as a factor in SARS-CoV-2 infection
This study proposed a comparison of the amount of hospitalized pregnant women during the COVID-19
pandemic and the amount of hospitalized women during the 2009 A-H1N1 Pandemic.
Based on this comparison, authors
indicate that despite a greater susceptibility of pregnant women to different
infections in the case of SARS-CoV-2, they appear to be protected. Compared to
2009 H1N1 epidemic, the ...
- Interest of botanicals for COVID-19
For many years, medicinal plants have been used for the management of viral diseases. The new COVID-19 epidemic is devoid of any effective and widely accepted medication. One lead to identify effective treatment is therefore medicinal plants.
Some plants have already been shown to be effective against other respiratory viruses, as influenza virus, respiratory syncytial virus ...
- The most promising flavonoids against COVID-19
Numerous flavonoids were found to have antiviral effects against SARS-and MERS-CoV by mainly inhibiting the enzymes 3-chymotrypsin-like protease (3CLpro) and papain-like protease (PLpro).
This review is specifically focused on the search for flavonoids, polyphenolic compounds, which are proven to be effective against human CoVs. The latest progress in research to identify flavonoids for antiviral therapy ...
- Black seed oil supplementation for improving pulmonary functions, inflammation, and oxidant-antioxidant imbalance in chronic obstructive pulmonary disease patients
This double-blind, randomized,
placebo-controlled study was conducted to examine whether supplementation
of black seed oil (BSO) can improve pulmonary function tests (PFTs),
inflammation, and oxidant-antioxidant markers in chronic obstructive pulmonary
disease (COPD) patients.
To do so, 91 COPD patients were
randomized to receive for 3 months either black seed oil (BSO) (2 g/d) or a
Results showed that BSO significantly decreased oxidant ...
- Identification of phytochemicals as potential therapeutic agents capable of inhibiting SARS-CoV-2 virus replication
This study aimed to study the binding potential of various phytochemicals present in multiple natural plant extract as a secondary metabolite to non-structural protein 15 (Nsp15) protein, a drug target known to play a crucial role in virulence of coronavirus. Results successfully demonstrate the binding of phytochemicals such as sarsasapogenin, ursonic acid, curcumin, ajmalicine, novobiocin, ...
- Pycnogenol® for supporting recovery and mitigating symptoms and long-term consequences resulting from a SARS-CoV2 infection in COVID-19 patients
COVID-19 can have severe, possibly persisting consequences, like endothelial dysfunction, microcirculatory problems, coagulopathy, cytokine storm and capillary leak syndrome. In various clinical studies, Pycnogenol® revealed positive effects relating to conditions that are also present in SARS-CoV2 infections.
Pycnogenol® improves endothelial health and microcirculation, normalizes platelet reactivity and shows anti-inflammatory effects. Therefore, in this review, authors ...