Cabinet Expert Scientifique et Réglementaire
Cabinet Expert Scientifique et Réglementaire
This randomized, controlled, in vivo study evaluated the effect of 50 mg/kg/d of lutein supplementation during 14 days, on ethanol-induced memory deficits in the object recognition task in adult Wistar rats. Rats were exposed to ethanol (3 g/kg/d), during 7 …
This randomized, open-label, placebo-controlled and crossover study examined the effects of fresh pear consumption (2 pears per day for 12 weeks) in middle-aged/older adults with metabolic syndrome. The effects of pear was compared to a calorie-matched control drink. Both supplementation …
This meta-analysis was performed with 17 randomized clinical trials and evaluated the effects of omega-3 supplementation among 3363 patients in the management of dry eye disease. Compared with placebo, omega-3 fatty acid supplementation decreased dry eye symptoms (p < 0.001) and corneal fluorescein staining (p = 0.032), …
The effects of alpha lipoid acid (ALA) on plasma lipids remains unclear due to contradictory results obtained in clinical trials. To clarify the effects of ALA, this meta-analysis includes 12 randomized and controlled trials assessing the effects of ALA on …
The aim of this observational study was to analyze the association between retinoid intake (total vitamin A, retinol, β-carotene, α-carotene, β-cryptoxanthin, lycopene, as wellas lutein and zeaxanthin) and self-reported gastrointestinal symptoms (daily number of bowel movements, and the presence of …
This randomized clinical trial aimed to evaluate the effect of isoflavone administration, either in conjunction with probiotic use or not, on the symptoms of genitourinary syndrome of menopause, and compare the effects with those of hormone therapy, in 60 postmenopausal …
The aim of this triple-blind, randomized placebo-controlled trial was to survey the effect of saffron supplementation on anti-HSP70, high-sensitivity C-reactive protein (hs-CRP) and spirometry test in patients with allergic asthma. To do so, 80 patients with mild and moderate allergic …
The aim of this parallel-group, triple-blind, placebo-controlled randomized clinical trial was to investigate the effect of alpha lipoic acid (ALA) on uterine wound healing after primary cesarean section (CS). To do so, 102 women undergoing pre-labor primary CS were randomized …
This in vivo study evaluated on atopic dermatitis-like hairless rat model the effects of 0.3 mL of lactic acid bacteria metabolites supplementation during 28 days on water content in the stratum corneum, transepidermal water loss (TEWL), ceramide AP content in …
The purpose of this randomized and placebo-controlled study was to examine the effects of a lemon balm supplementation in subjects with type 2 diabetes. 62 patients have been recruited and have received for 12 weeks either a placebo or a …
